rs11554495, KRT8

N. diseases: 19
Disease: Liver Failure, Acute ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Liver Failure, Acute
CUI: C0162557
Disease: Liver Failure, Acute
0.010 GeneticVariation BEFREE Expression of human K8 variants G62C, R341H, or R341C in mice predisposes to acute APAP hepatotoxicity, thereby providing direct evidence for the importance of these variants in human acute liver failure. 25963979 2015