rs2221903, IL21-AS1;IL21

N. diseases: 12
Disease: Hepatitis B ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.020 GeneticVariation BEFREE Our findings suggest that the rs12508721T/C and rs2221903A/G polymorphisms of IL-21 gene are associated with the susceptibility of HBV-related HCC and chronic HBV infection. 27122304 2016
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.020 GeneticVariation BEFREE It is suggested that IL21 rs2221903 and IL21R rs3093301 polymorphisms may, independently or interactively, affect the susceptibility to and/or persistence of HBV infection potentially through altering IL-21 and IgE production. 23354321 2013