rs2293152, STAT3

N. diseases: 10
Disease: Liver carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.020 GeneticVariation BEFREE However, no significant association between rs2293152 and HCC development was observed. 26745093 2015
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.020 GeneticVariation BEFREE In multivariate regression analyses, multiplicative interaction of rs1053004 with T1674C/G significantly increased HCC risk, whereas rs2293152 and A1726C interaction reduced it, adjusting for covariates including HBV mutations in the enhancer II/basal core promoter/precore region; the interaction of rs4796793 with preS2 start codon mutation significantly increased HCC risk, adjusting for covariates including HBV mutations in the preS region. 23386590 2013