Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PAPSS2 O95340 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Enzyme 2.0E-10 0.682 0.462 37 12
HACD1 B0YJ81 3-hydroxyacyl-CoA dehydratase 1 1.3E-09 0.539 0.846 160 0
HAAO P46952 3-hydroxyanthranilate 3,4-dioxygenase 1.1E-08 0.644 0.538 47 4
KDSR Q06136 3-ketodihydrosphingosine reductase 0.12 0.674 0.538 52 4
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 266 96
ABHD5 Q8WTS1 abhydrolase domain containing 5 6.4E-07 0.641 0.538 76 8
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 395 37
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769 159 165
ACD Q96AP0 ACD shelterin complex subunit and telomerase recruitment factor 1.1E-12 0.603 0.731 96 7
ACP5 P13686 acid phosphatase 5, tartrate resistant 7.9E-02 0.561 0.731 130 13
ACTA1 P68133 actin alpha 1, skeletal muscle Cellular structure 1.1E-06 0.540 0.769 217 59
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 1110 39
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462 100 7
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846 149 57
ADNP Q9H2P0 activity dependent neuroprotector homeobox 1.00 0.561 0.808 171 23
ADAMTS10 Q9H324 ADAM metallopeptidase with thrombospondin type 1 motif 10 Enzyme 0.84 0.641 0.500 67 12
ADAMTS17 Q8TE56 ADAM metallopeptidase with thrombospondin type 1 motif 17 Enzyme 2.8E-15 0.678 0.385 37 24
ADAMTS2 O95450 ADAM metallopeptidase with thrombospondin type 1 motif 2 Enzyme 0.97 0.579 0.808 138 13
ADAMTSL2 Q86TH1 ADAMTS like 2 Enzyme 1.6E-03 0.666 0.346 61 12
AP1S2 P56377 adaptor related protein complex 1 subunit sigma 2 Transporter 0.87 0.631 0.615 93 8
AP3B2 Q13367 adaptor related protein complex 3 subunit beta 2 Transporter 0.77 0.691 0.346 60 10
AP4B1 Q9Y6B7 adaptor related protein complex 4 subunit beta 1 Transporter 1.3E-09 0.631 0.654 79 16
AP4E1 Q9UPM8 adaptor related protein complex 4 subunit epsilon 1 Receptor 2.8E-03 0.656 0.385 72 19
AP4M1 O00189 adaptor related protein complex 4 subunit mu 1 Extracellular structure 4.5E-17 0.638 0.500 78 12