Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 239
PEX6 Q13608 peroxisomal biogenesis factor 6 6.3E-06 0.547 0.731 212
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 169
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 168
WDR35 Q9P2L0 WD repeat domain 35 1.0E-22 0.525 0.692 160
CDH23 Q9H251 cadherin related 23 3.2E-06 0.539 0.769 156
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 135
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885 126
GNPTAB Q3T906 N-acetylglucosamine-1-phosphate transferase subunits alpha and beta 7.7E-19 0.592 0.731 120
VAMP1 P23763 vesicle associated membrane protein 1 3.9E-03 0.628 0.538 112
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 108
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846 106
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 97
ATP13A2 Q9NQ11 ATPase cation transporting 13A2 9.0E-09 0.566 0.577 97
WDPCP O95876 WD repeat containing planar cell polarity effector 1.1E-10 0.576 0.769 93
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 92
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 88
CDH11 P55287 cadherin 11 1.00 0.512 0.808 87
ARHGAP31 Q2M1Z3 Rho GTPase activating protein 31 1.00 0.581 0.615 87
GRN P28799 granulin precursor 7.0E-02 0.435 0.846 86
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 84
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462 84
CFH P08603 complement factor H 0.86 0.441 0.885 83
CANT1 Q8WVQ1 calcium activated nucleotidase 1 2.5E-06 0.619 0.731 79