Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 17
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538 5
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 8
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 16
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 20
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731 6
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 21
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846 7
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 26
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
APLN Q9ULZ1 apelin 0.46 0.497 0.769 7
ALOX12 P18054 arachidonate 12-lipoxygenase, 12S type Enzyme 1.4E-15 0.558 0.692 5
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846 4
ARRB1 P49407 arrestin beta 1 Enzyme modulator 0.99 0.588 0.846 5
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 14
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731 13
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 60
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 39
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26