Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 58
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 60
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 22
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 18
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 2
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
LEP P41159 leptin 0.46 0.349 0.846 28
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 17
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 27
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 25
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 59
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 16
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 45
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 12
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 69
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 11
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 26