Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 95 5
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 124 58
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 138 9
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 119 12
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 138 40
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 113 95
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 48 35
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 83 37
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 98 8
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 81 1
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 31 16
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 44 22
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 57 2505
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 32 16
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 120 21
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 73 19
CDH1 P12830 cadherin 1 0.15 0.401 0.808 73 158
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 97 0
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 48 0
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808 37 3
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885 49 1