Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1519 11
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1314 146
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1174 54
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1074 19
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1034 6
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
IL2 P60568 interleukin 2 0.48 0.336 0.885 950 5
LEP P41159 leptin 0.46 0.349 0.846 931 15
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
H3P10 H3 histone pseudogene 10 0.350 0.846 769 0
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 754 47
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 749 15
MIR21 microRNA 21 0.363 0.846 726 2
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24