Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 40
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 22
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 11
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 45
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 45
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 18
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 8
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 58
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 16
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 23
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26