Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 1558 50
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 1349 384
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 960 48
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 739 23
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 706 308
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808 511 0
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 535 65
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 487 9
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846 664 387
STS P08842 steroid sulfatase Enzyme 0.81 0.431 0.846 382 16
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 417 14
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846 448 30
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846 372 215
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 469 292
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808 353 29
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 341 22
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808 362 47
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808 317 64
CALCR P30988 calcitonin receptor G-protein coupled receptor 3.1E-09 0.464 0.846 282 12
GPC3 P51654 glypican 3 1.00 0.466 0.808 311 16
NF2 P35240 neurofibromin 2 1.00 0.468 0.885 312 54
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 314 21
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769 346 10