Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 303
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 245
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 83
PTCH1 Q13635 patched 1 1.00 0.398 0.885 143
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808 73
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 154
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846 49
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 27
ELN P15502 elastin 2.1E-14 0.415 0.885 248
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808 43
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846 119
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808 132
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808 101
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846 94
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 219
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808 105
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808 77
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 85
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808 98
BEST1 O76090 bestrophin 1 Ion channel 1.8E-12 0.465 0.885 56
GPC3 P51654 glypican 3 1.00 0.466 0.808 126
DHDDS Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 0.25 0.468 0.885 82
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846 142
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731 74