Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 1511 83
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 1193 57
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 960 48
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808 320 266
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 317 18
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 306 19
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 300 17
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769 217 201
DCAF1 Q9Y4B6 DDB1 and CUL4 associated factor 1 1.00 0.601 0.731 73 5
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1119 24
ETV5 P41161 ETS variant transcription factor 5 Transcription factor 1.00 0.565 0.731 121 11
PIAS1 O75925 protein inhibitor of activated STAT 1 1.00 0.633 0.731 54 2
CYLD Q9NQC7 CYLD lysine 63 deubiquitinase Enzyme 1.00 0.498 0.846 211 34
ATN1 P54259 atrophin 1 1.00 0.409 0.885 499 6
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885 480 10
SEMA6A Q9H2E6 semaphorin 6A Signaling 1.00 0.486 0.808 211 4
MSN P26038 moesin Cellular structure 1.00 0.534 0.769 140 3
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 1083 13
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 257 70
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 487 48
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 687 76
AGFG1 P52594 ArfGAP with FG repeats 1 0.99 0.569 0.769 100 4
SUV39H1 O43463 suppressor of variegation 3-9 homolog 1 0.99 0.595 0.577 77 1