Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1801 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1174 54
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1074 19
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 1049 62
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 1002 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
IL2 P60568 interleukin 2 0.48 0.336 0.885 950 5
LEP P41159 leptin 0.46 0.349 0.846 931 15
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 873 39
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 824 13
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 783 28
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 750 18
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 722 24
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 702 98
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 701 52
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64