Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769 16
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885 12
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769 10
LEP P41159 leptin 0.46 0.349 0.846 10
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 10
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 10
SAT1 P21673 spermidine/spermine N1-acetyltransferase 1 0.87 0.539 0.808 10
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885 9
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846 9
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 9
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731 9
IL6 P05231 interleukin 6 0.32 0.248 0.962 8
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846 8
GAP43 P17677 growth associated protein 43 2.1E-02 0.564 0.731 7
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885 7
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 7
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808 7
ADCY7 P51828 adenylate cyclase 7 9.5E-07 0.656 0.462 6
ADCY5 O95622 adenylate cyclase 5 1.00 0.617 0.577 5
NTS P30990 neurotensin 3.9E-05 0.517 0.769 5
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 5
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923 5
MPDZ O75970 multiple PDZ domain crumbs cell polarity complex component 5.8E-38 0.638 0.500 5
PDE10A Q9Y233 phosphodiesterase 10A 1.00 0.619 0.615 4