Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 178
IFNA2 P01563 interferon alpha 2 0.442 0.885 169
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 105
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 77
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57
CDH1 P12830 cadherin 1 0.15 0.401 0.808 57
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 52
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 52
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731 44
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 39
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 31
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808 29
UMPS P11172 uridine monophosphate synthetase 1.1E-04 0.584 0.615 28
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 27
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 26
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846 24
IFNA1 P01562 interferon alpha 1 0.371 0.923 24
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846 23
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 23
CD9 P21926 CD9 molecule 4.7E-03 0.528 0.769 21
TCN2 P20062 transcobalamin 2 1.0E-06 0.578 0.615 20
FLCN Q8NFG4 folliculin 0.79 0.537 0.885 19