Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FLNA P21333 filamin A 1.00 0.419 0.846 298
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808 213
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 205
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 202
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 193
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 189
POMT1 Q9Y6A1 protein O-mannosyltransferase 1 4.2E-17 0.525 0.615 177
FKRP Q9H9S5 fukutin related protein 9.8E-06 0.513 0.731 177
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731 162
GP1BB P13224 glycoprotein Ib platelet subunit beta 0.51 0.524 0.769 158
POMT2 Q9UKY4 protein O-mannosyltransferase 2 9.4E-12 0.544 0.615 157
FKTN O75072 fukutin 8.7E-07 0.511 0.692 151
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769 151
GPC4 O75487 glypican 4 0.93 0.547 0.769 148
POMGNT1 Q8WZA1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.9E-20 0.537 0.538 146
CSPP1 Q1MSJ5 centrosome and spindle pole associated protein 1 3.3E-29 0.544 0.769 146
TMEM216 Q9P0N5 transmembrane protein 216 1.9E-03 0.544 0.615 143
PTCH1 Q13635 patched 1 1.00 0.398 0.885 143
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846 142
KIF7 Q2M1P5 kinesin family member 7 2.3E-22 0.528 0.731 137
GMPPB Q9Y5P6 GDP-mannose pyrophosphorylase B 8.4E-07 0.578 0.538 135
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769 135
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769 134
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 134