Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 6 19
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808 2 2
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 3 31
MYLK Q15746 myosin light chain kinase Kinase 9.2E-12 0.510 0.846 2 2
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 1.00 0.552 0.731 6 2
ULK1 O75385 unc-51 like autophagy activating kinase 1 Kinase 0.99 0.564 0.769 2 1
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577 1 1
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 5 5
MAP3K14 Q99558 mitogen-activated protein kinase kinase kinase 14 Kinase 0.608 0.769 1 0
DAPK3 O43293 death associated protein kinase 3 Kinase 6.6E-03 0.612 0.654 2 0
EPHB6 O15197 EPH receptor B6 Kinase 1.2E-07 0.619 0.538 3 0
TNK2 Q07912 tyrosine kinase non receptor 2 Kinase 8.2E-12 0.623 0.538 4 2
WNK4 Q96J92 WNK lysine deficient protein kinase 4 Kinase 6.9E-25 0.644 0.538 3 4
ALPK1 Q96QP1 alpha kinase 1 Kinase 1.0E-19 0.644 0.615 1 0
MATK P42679 megakaryocyte-associated tyrosine kinase Kinase 2.3E-06 0.656 0.423 2 1
CDK14 O94921 cyclin dependent kinase 14 Kinase 2.5E-08 0.659 0.423 1 1
HCK P08631 HCK proto-oncogene, Src family tyrosine kinase Kinase 2.0E-02 0.663 0.500 1 0
RPS6KB2 Q9UBS0 ribosomal protein S6 kinase B2 Kinase 6.0E-21 0.678 0.538 1 1
SPEG Q15772 striated muscle enriched protein kinase Kinase 0.92 0.686 0.385 3 4
NEK10 Q6ZWH5 NIMA related kinase 10 Kinase 7.7E-10 0.705 0.269 2 1
RYK P34925 receptor like tyrosine kinase Kinase 0.99 0.705 0.423 1 1
NRBP1 Q9UHY1 nuclear receptor binding protein 1 Kinase 1.00 0.729 0.346 1 1
CDKL2 Q92772 cyclin dependent kinase like 2 Kinase 3.1E-17 0.751 0.346 1 1