Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HMGCL P35914 3-hydroxy-3-methylglutaryl-CoA lyase Enzyme 2.6E-06 0.691 0.462 2
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 2
ATIC P31939 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Enzyme 3.0E-19 0.576 0.731 2
PTS Q03393 6-pyruvoyltetrahydropterin synthase 6.5E-06 0.636 0.654 3
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 6
AKAP6 Q13023 A-kinase anchoring protein 6 1.00 0.695 0.538 1
ACTL6A O96019 actin like 6A Cellular structure 1.00 0.678 0.346 3
ACTL6B O94805 actin like 6B Cellular structure 2.8E-04 0.656 0.462 6
ACBD6 Q9BR61 acyl-CoA binding domain containing 6 2.3E-06 0.890 0.269 1
ACOT9 Q9Y305 acyl-CoA thioesterase 9 Enzyme 6.8E-09 0.931 0.154 1
AP1B1 Q10567 adaptor related protein complex 1 subunit beta 1 Transporter 1.00 0.716 0.385 6
AP2M1 Q96CW1 adaptor related protein complex 2 subunit mu 1 Extracellular structure 1.00 0.751 0.231 6
ADSL P30566 adenylosuccinate lyase Enzyme 8.9E-12 0.631 0.654 3
ARL13B Q3SXY8 ADP ribosylation factor like GTPase 13B 2.7E-09 0.631 0.538 4
ADPRS Q9NX46 ADP-ribosylserine hydrolase 5.8E-04 0.743 0.308 5
AFF3 P51826 AF4/FMR2 family member 3 Transcription factor 1.00 0.623 0.692 2
ALDH3A2 P51648 aldehyde dehydrogenase 3 family member A2 9.4E-06 0.619 0.769 3
ALDH4A1 P30038 aldehyde dehydrogenase 4 family member A1 1.4E-05 0.792 0.231 2
ALG13 Q9NP73 ALG13 UDP-N-acetylglucosaminyltransferase subunit 1.00 0.631 0.577 4
ALG14 Q96F25 ALG14 UDP-N-acetylglucosaminyltransferase subunit 9.4E-04 0.722 0.308 3
ALKBH8 Q96BT7 alkB homolog 8, tRNA methyltransferase 2.0E-04 0.716 0.423 4
AGMO Q6ZNB7 alkylglycerol monooxygenase 6.8E-26 0.780 0.423 3
FUCA1 P04066 alpha-L-fucosidase 1 2.7E-08 0.623 0.577 3
ACY1 Q03154 aminoacylase 1 6.9E-09 0.653 0.577 2