Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 979 70
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 957 6
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 202 8
ADAMTS1 Q9UHI8 ADAM metallopeptidase with thrombospondin type 1 motif 1 Enzyme 0.72 0.555 0.654 99 4
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 354 1
ADM2 Q7Z4H4 adrenomedullin 2 Signaling 2.0E-02 0.711 0.462 33 2
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769 115 10
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 632 35
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 381 26
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923 526 3
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923 529 6
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1011 29
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769 218 12
ALDH2 P05091 aldehyde dehydrogenase 2 family member Enzyme 3.4E-10 0.457 0.885 287 18
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885 278 12
ANGPT1 Q15389 angiopoietin 1 Signaling 0.95 0.446 0.808 317 5
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 420 13
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846 257 13
APLN Q9ULZ1 apelin 0.46 0.497 0.769 218 11
APOL1 O14791 apolipoprotein L1 Transporter 5.1E-06 0.547 0.615 107 6
AQP2 P41181 aquaporin 2 Ion channel 2.5E-06 0.581 0.769 75 22
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769 194 0
ARRB1 P49407 arrestin beta 1 Enzyme modulator 0.99 0.588 0.846 81 0
ARRB2 P32121 arrestin beta 2 Enzyme modulator 0.51 0.561 0.769 104 3