Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 194 9
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 399 8
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 154 15
HACD1 B0YJ81 3-hydroxyacyl-CoA dehydratase 1 1.3E-09 0.539 0.846 160 0
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 77 0
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 102 9
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 376 7
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 229 9
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 245 30
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 207 22
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 104 1
PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Enzyme 2.1E-09 0.666 0.346 40 3
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 313 38
AKAP1 Q92667 A-kinase anchoring protein 1 Enzyme 0.74 0.678 0.577 35 0
AKAP4 Q5JQC9 A-kinase anchoring protein 4 0.99 0.700 0.269 29 0
AKIP1 Q9NQ31 A-kinase interacting protein 1 1.1E-05 0.705 0.308 29 3
ABHD11-AS1 ABHD11 antisense RNA 1 (tail to tail) 0.722 0.192 24 1
ABI1 Q8IZP0 abl interactor 1 Enzyme modulator 0.64 0.641 0.538 56 1
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 395 37
ABL2 P42684 ABL proto-oncogene 2, non-receptor tyrosine kinase Kinase 3.6E-07 0.619 0.654 56 1
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 443 160
ABRACL Q9P1F3 ABRA C-terminal like 0.24 0.931 0.077 3 0
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846 241 26
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 418 6