Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 117 2
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 396 7
ADO Q96SZ5 2-aminoethanethiol dioxygenase 0.48 0.670 0.538 37 1
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 38 0
BDH2 Q9BUT1 3-hydroxybutyrate dehydrogenase 2 8.5E-08 0.700 0.462 26 0
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 66 0
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 361 4
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 91 1
PFKFB4 Q16877 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Enzyme 2.1E-09 0.666 0.346 36 0
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 266 37
AKAP12 Q02952 A-kinase anchoring protein 12 3.6E-02 0.566 0.615 86 1
AKAP13 Q12802 A-kinase anchoring protein 13 0.93 0.626 0.615 53 3
AKIP1 Q9NQ31 A-kinase interacting protein 1 1.1E-05 0.705 0.308 26 0
ARAF P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 0.96 0.619 0.654 48 2
ABHD11-AS1 ABHD11 antisense RNA 1 (tail to tail) 0.722 0.192 24 0
ABI3 Q9P2A4 ABI family member 3 Enzyme modulator 5.0E-05 0.716 0.231 21 2
ABI1 Q8IZP0 abl interactor 1 Enzyme modulator 0.64 0.641 0.538 49 0
ABI2 Q9NYB9 abl interactor 2 Enzyme modulator 0.43 0.700 0.423 26 0
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 309 21
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769 116 4
AIM2 O14862 absent in melanoma 2 2.2E-09 0.521 0.769 165 1
ACAT2 Q9BWD1 acetyl-CoA acetyltransferase 2 Enzyme 5.5E-07 0.686 0.462 24 1
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846 227 14
ASCL1 P50553 achaete-scute family bHLH transcription factor 1 Transcription factor 0.68 0.552 0.692 95 0