Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 117 2
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 396 7
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 138 4
PAPSS1 O43252 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Enzyme 6.3E-08 0.839 0.154 10 0
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 66 0
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 83 3
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 361 4
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 114 5
AZI2 Q9H6S1 5-azacytidine induced 2 6.9E-03 0.760 0.577 19 2
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 196 21
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 159 16
OPLAH O14841 5-oxoprolinase, ATP-hydrolysing Enzyme 7.0E-17 0.792 0.308 5 2
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 91 1
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 266 37
AKAP4 Q5JQC9 A-kinase anchoring protein 4 0.99 0.700 0.269 29 0
AKIP1 Q9NQ31 A-kinase interacting protein 1 1.1E-05 0.705 0.308 26 0
ARAF P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 0.96 0.619 0.654 48 2
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 309 21
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769 116 4
AIM2 O14862 absent in melanoma 2 2.2E-09 0.521 0.769 165 1
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846 227 14
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 324 3
ASCL1 P50553 achaete-scute family bHLH transcription factor 1 Transcription factor 0.68 0.552 0.692 95 0
ANP32B Q92688 acidic nuclear phosphoprotein 32 family member B Enzyme modulator 0.96 0.541 0.731 117 0