Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731 21
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 20
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 16
COL4A5 P29400 collagen type IV alpha 5 chain 1.00 0.553 0.654 14
FLNA P21333 filamin A 1.00 0.419 0.846 14
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846 12
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 12
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 12
ZNF292 O60281 zinc finger protein 292 Enzyme 1.00 0.695 0.423 12
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846 10
COL5A2 P05997 collagen type V alpha 2 chain 1.00 0.568 0.731 10
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 10
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846 9
MYH9 P35579 myosin heavy chain 9 1.00 0.505 0.808 9
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769 8
COL5A1 P20908 collagen type V alpha 1 chain 1.00 0.536 0.769 8
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 8
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 8
MED13 Q9UHV7 mediator complex subunit 13 1.00 0.711 0.538 8
MED12L Q86YW9 mediator complex subunit 12L Transcription factor 1.00 0.839 0.269 8
TET3 O43151 tet methylcytosine dioxygenase 3 1.00 0.633 0.615 8
CACNA1E Q15878 calcium voltage-gated channel subunit alpha1 E Ion channel 1.00 0.650 0.577 7
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 7
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 7