Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1410 15
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1034 19
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1030 52
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
IL2 P60568 interleukin 2 0.48 0.336 0.885 894 4
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 816 57
LEP P41159 leptin 0.46 0.349 0.846 807 13
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 717 26
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 715 13
MIR21 microRNA 21 0.363 0.846 705 2
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 704 15
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 702 42
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 673 18
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 665 33
IFNA1 P01562 interferon alpha 1 0.371 0.923 646 6
IFNA13 P01562 interferon alpha 13 0.374 0.923 646 4
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 641 11