Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 74 50
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 69 53
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 53 30
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 52 70
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
TSBP1-AS1 TSBP1 and BTNL2 antisense RNA 1 0.638 0.692 44 49
IRF1-AS1 Q8N8D9 IRF1 antisense RNA 1 4.2E-03 0.670 0.385 41 26
MIR4435-2HG MIR4435-2 host gene 0.604 0.692 38 56
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 36 16
CASC15 cancer susceptibility 15 0.603 0.577 35 41
ZFHX3 Q15911 Q6ZP98 zinc finger homeobox 3 0.45 0.621 0.654 32 34
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 31 11
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 30 48
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 30 9
GBAP1 glucosylceramidase beta pseudogene 1 0.623 0.538 29 8
ASTN2 O75129 astrotactin 2 1.00 0.666 0.462 26 32
EBF1 Q9UH73 EBF transcription factor 1 1.00 0.584 0.654 24 42
SOX6 P35712 SRY-box transcription factor 6 1.00 0.578 0.615 24 41
TNXB P22105 tenascin XB 1.9E-02 0.572 0.731 24 26
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 24 12
COL4A2 P08572 collagen type IV alpha 2 chain 3.6E-15 0.563 0.654 23 22