Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 450 16
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 485 114
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885 311 9
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 1157 8
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 514 6
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885 631 9
CREB3L1 Q96BA8 cAMP responsive element binding protein 3 like 1 0.98 0.601 0.615 88 12
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 304 17
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846 518 2
CSPG4 Q6UVK1 chondroitin sulfate proteoglycan 4 2.6E-05 0.599 0.615 75 1
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 875 79
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923 378 3
F2RL1 P55085 F2R like trypsin receptor 1 G-protein coupled receptor 1.5E-04 0.480 0.769 256 4
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885 447 99
GORASP1 Q9BQQ3 golgi reassembly stacking protein 1 2.0E-02 0.428 0.846 369 7
GRN P28799 granulin precursor 7.0E-02 0.435 0.846 412 66
GAP43 P17677 growth associated protein 43 2.1E-02 0.564 0.731 109 0
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885 671 22
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 1044 15
IFNB1 P01574 interferon beta 1 0.421 0.846 426 4
LINGO1 Q96FE5 leucine rich repeat and Ig domain containing 1 Receptor 0.99 0.682 0.385 44 22
LIF P15018 LIF interleukin 6 family cytokine Signaling 0.52 0.483 0.769 236 4
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 1021 43