Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 52 70
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
JAZF1 Q86VZ6 JAZF zinc finger 1 0.90 0.582 0.654 49 45
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769 46 41
TSBP1-AS1 TSBP1 and BTNL2 antisense RNA 1 0.638 0.692 44 49
ZMIZ1 Q9ULJ6 zinc finger MIZ-type containing 1 1.00 0.588 0.615 40 33
DLEU1 O43261 deleted in lymphocytic leukemia 1 0.47 0.569 0.692 38 64
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 38 13
MIR4435-2HG MIR4435-2 host gene 0.604 0.692 38 56
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 35 48
CASC15 cancer susceptibility 15 0.603 0.577 35 41
CDKAL1 Q5VV42 CDK5 regulatory subunit associated protein 1 like 1 1.6E-02 0.617 0.615 33 44
HECTD4 Q9Y4D8 HECT domain E3 ubiquitin protein ligase 4 1.00 0.700 0.462 31 11
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 30 48
CLEC16A Q2KHT3 C-type lectin domain containing 16A 0.28 0.612 0.654 29 38
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 29 33
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 29 32
LRMDA Q9H2I8 leucine rich melanocyte differentiation associated 2.6E-04 0.659 0.577 29 23
PNKD Q8N490 PNKD metallo-beta-lactamase domain containing 4.1E-08 0.615 0.615 28 17
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 27 23
ASTN2 O75129 astrotactin 2 1.00 0.666 0.462 26 32
CADM2 Q8N3J6 cell adhesion molecule 2 0.89 0.670 0.538 26 72
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808 26 30