Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1533 21
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 1214 67
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1050 26
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1034 19
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 1030 52
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
IL2 P60568 interleukin 2 0.48 0.336 0.885 894 4
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 717 26
MIR21 microRNA 21 0.363 0.846 705 2
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 702 42
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 673 18
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962 664 32
IFNA1 P01562 interferon alpha 1 0.371 0.923 646 6
IFNA13 P01562 interferon alpha 13 0.374 0.923 646 4
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 641 11
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846 622 12
VIM P08670 vimentin 0.71 0.372 0.846 592 2
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 583 19