Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769 20
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577 9
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538 5
ACO1 P21399 aconitase 1 Enzyme 3.8E-18 0.628 0.577 6
ACADVL P49748 acyl-CoA dehydrogenase very long chain Enzyme 4.2E-15 0.653 0.654 5
ADAMTS13 Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 5.1E-15 0.496 0.769 6
CIDEB Q9UHD4 cell death inducing DFFA like effector b 8.2E-15 0.861 0.154 4
ACADM P11310 acyl-CoA dehydrogenase medium chain Enzyme 2.1E-12 0.638 0.462 3
DGAT2 Q96PD7 diacylglycerol O-acyltransferase 2 Enzyme 8.4E-12 0.686 0.423 7
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808 18
SIRT4 Q9Y6E7 sirtuin 4 Epigenetic regulator 6.9E-10 0.603 0.654 4
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 16
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 26
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 24
SIRT2 Q8IXJ6 sirtuin 2 Epigenetic regulator 2.3E-08 0.510 0.769 6
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 31
PHYH O14832 phytanoyl-CoA 2-hydroxylase 2.4E-06 0.659 0.577 3
HADHA P40939 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Enzyme 4.4E-06 0.569 0.769 4
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 20
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
CYP8B1 Q9UNU6 cytochrome P450 family 8 subfamily B member 1 2.1E-05 0.711 0.269 5
RARRES2 Q99969 retinoic acid receptor responder 2 2.7E-05 0.519 0.731 6