Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HPGD P15428 15-hydroxyprostaglandin dehydrogenase 1.4E-05 0.516 0.731 194 9
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 399 8
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 216 12
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 154 15
HMGCS2 P54868 3-hydroxy-3-methylglutaryl-CoA synthase 2 4.3E-14 0.666 0.577 52 9
HACD4 Q5VWC8 3-hydroxyacyl-CoA dehydratase 4 2.1E-05 0.931 0.038 4 0
OXCT1 P55809 3-oxoacid CoA-transferase 1 Enzyme 4.7E-03 0.686 0.423 33 13
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 77 0
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 127 20
HPD P32754 4-hydroxyphenylpyruvate dioxygenase Enzyme 5.3E-04 0.573 0.769 102 9
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 376 7
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 229 9
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 245 30
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 207 22
PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 Kinase 2.4E-07 0.760 0.231 22 4
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 104 1
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 313 38
AKAP1 Q92667 A-kinase anchoring protein 1 Enzyme 0.74 0.678 0.577 35 0
AKAP10 O43572 A-kinase anchoring protein 10 0.11 0.760 0.308 28 18
AKAP11 Q9UKA4 A-kinase anchoring protein 11 0.98 1.000 0.077 2 0
AKAP12 Q02952 A-kinase anchoring protein 12 3.6E-02 0.566 0.615 99 8
AKAP13 Q12802 A-kinase anchoring protein 13 0.93 0.626 0.615 73 15
AKAP4 Q5JQC9 A-kinase anchoring protein 4 0.99 0.700 0.269 29 0
AKAP9 Q99996 A-kinase anchoring protein 9 4.5E-17 0.638 0.385 60 18