Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 239
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 218
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 209
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 200
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 190
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731 175
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769 174
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 168
POMT2 Q9UKY4 protein O-mannosyltransferase 2 9.4E-12 0.544 0.615 163
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 159
HBB P68871 hemoglobin subunit beta 1.2E-09 0.494 0.808 151
ANKRD11 Q6UB99 ankyrin repeat domain 11 1.00 0.556 0.808 145
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692 142
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 135
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808 132
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769 127
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 114
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846 112
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846 111
KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 1.00 0.592 0.731 110
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 108
CPLX1 O14810 complexin 1 0.82 0.576 0.654 107