Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 238
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 224
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 182
IFNA2 P01563 interferon alpha 2 0.442 0.885 169
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168
IFNG P01579 interferon gamma 0.47 0.288 0.962 157
INS P01308 insulin 0.30 0.445 0.923 153
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 135
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 135
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 111
LEP P41159 leptin 0.46 0.349 0.846 104
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 92
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 65
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 59
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769 48
VIM P08670 vimentin 0.71 0.372 0.846 48
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 44
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 40
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769 40
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 37
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 37
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923 36