Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 604 19
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846 597 65
FLNA P21333 filamin A 1.00 0.419 0.846 571 85
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 496 96
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846 283 99
SOST Q9BQB4 sclerostin 0.87 0.474 0.808 270 4
TNFRSF11A Q9Y6Q6 TNF receptor superfamily member 11a 8.8E-03 0.480 0.846 270 22
PCYT1A P49585 phosphate cytidylyltransferase 1, choline, alpha 2.0E-05 0.485 0.885 256 12
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769 248 82
RMRP RNA component of mitochondrial RNA processing endoribonuclease 0.519 0.731 239 77
COMP P49747 cartilage oligomeric matrix protein 1.3E-09 0.503 0.808 230 31
MIR17HG Q75NE6 miR-17-92a-1 cluster host gene 0.483 0.808 224 7
GPC4 O75487 glypican 4 0.93 0.547 0.769 181 8
MARCKSL1 P49006 MARCKS like 1 1.4E-02 0.508 0.731 169 1
ANK1 P16157 ankyrin 1 1.00 0.540 0.885 166 49
WLS Q5T9L3 Wnt ligand secretion mediator 2.0E-02 0.513 0.731 166 33
TCTN3 Q6NUS6 tectonic family member 3 4.2E-12 0.566 0.615 136 6
GYPA P02724 glycophorin A (MNS blood group) 1.1E-03 0.538 0.885 136 5
AMER1 Q5JTC6 APC membrane recruitment protein 1 0.85 0.570 0.654 134 8
DMP1 Q13316 dentin matrix acidic phosphoprotein 1 1.5E-07 0.556 0.615 134 6
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731 127 11
COL9A3 Q14050 collagen type IX alpha 3 chain 3.3E-12 0.569 0.769 125 9