Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL2 P60568 interleukin 2 0.48 0.336 0.885 3 3
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 39 22
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 53 31
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 37 36
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 38 29
CD28 P10747 CD28 molecule 0.36 0.436 0.885 5 4
ETS1 P14921 ETS proto-oncogene 1, transcription factor Transcription factor 0.78 0.444 0.731 24 18
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769 22 24
STAT4 Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 0.77 0.471 0.769 30 28
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808 23 34
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846 3 11
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
IRF4 Q15306 interferon regulatory factor 4 Transcription factor 0.86 0.491 0.769 29 10
DAG1 Q14118 dystroglycan 1 Receptor 0.98 0.498 0.808 21 5
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731 1 1
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 19 11
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
CCR3 P51677 C-C motif chemokine receptor 3 G-protein coupled receptor 1.3E-04 0.527 0.808 14 9
TNFSF15 O95150 TNF superfamily member 15 Signaling 2.8E-03 0.531 0.692 18 8
WNT3 P56703 Wnt family member 3 Signaling 0.88 0.536 0.808 13 10
CIITA P33076 class II major histocompatibility complex transactivator 1.4E-07 0.536 0.808 3 2
PTPN2 P17706 protein tyrosine phosphatase non-receptor type 2 1.00 0.538 0.692 28 17
BACH2 Q9BYV9 BTB domain and CNC homolog 2 1.00 0.539 0.731 41 29
CD247 P20963 CD247 molecule 1.7E-02 0.539 0.731 12 11