Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HMGCL P35914 3-hydroxy-3-methylglutaryl-CoA lyase Enzyme 2.6E-06 0.691 0.462 75 30
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 395 37
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692 176 30
ADAMTS13 Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 5.1E-15 0.496 0.769 229 83
ADA2 Q9NZK5 adenosine deaminase 2 Enzyme 8.1E-08 0.545 0.846 165 22
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 450 16
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 519 41
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 854 163
ANTXR2 P58335 ANTXR cell adhesion molecule 2 Receptor 8.7E-02 0.568 0.808 143 27
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 339 122
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885 268 8
RARS1 P54136 arginyl-tRNA synthetase 1 3.3E-08 0.604 0.538 94 9
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 420 9
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885 392 7
BLVRB P30043 biliverdin reductase B Enzyme 4.2E-06 0.695 0.423 31 2
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769 320 3
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846 626 21
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 739 23
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923 487 9
CPB2 Q96IY4 carboxypeptidase B2 Enzyme 2.7E-17 0.536 0.846 148 11
CSNK1A1 P48729 casein kinase 1 alpha 1 Kinase 1.00 0.686 0.385 36 2
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769 172 33
CD177 Q8N6Q3 CD177 molecule 0.595 0.654 75 6