Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808 266 5
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 259 47
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846 254 0
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 248 5
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808 248 12
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 238 38
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808 238 6
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885 237 5
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846 227 14
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885 220 14
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 215 6
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 202 8
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 202 3
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885 201 10
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 199 5
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769 197 5
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 196 6
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808 196 6
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769 189 8
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808 189 3
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808 187 53
NF2 P35240 neurofibromin 2 1.00 0.468 0.885 183 5
SMARCA1 P28370 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 Enzyme 1.00 0.504 0.808 181 0
VCAN P13611 versican Extracellular structure 1.00 0.497 0.808 180 5