Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 534 52
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 526 11
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 514 45
MIR146A microRNA 146a 0.398 0.885 492 3
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846 477 9
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885 474 18
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 452 15
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846 425 5
IL23A Q9NPF7 interleukin 23 subunit alpha Signaling 0.36 0.415 0.846 423 2
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846 421 6
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 416 6
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 393 9
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808 378 11
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 352 25
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962 339 11
GRN P28799 granulin precursor 7.0E-02 0.435 0.846 334 34
LTA P01374 lymphotoxin alpha Signaling 0.20 0.434 0.885 329 20
CD19 P15391 CD19 molecule 0.90 0.430 0.885 328 2
IL21 Q9HBE4 interleukin 21 0.63 0.441 0.769 306 5
MYDGF Q969H8 myeloid derived growth factor 3.5E-06 0.451 0.846 293 2
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808 293 0
IL9 P15248 interleukin 9 8.1E-07 0.461 0.846 283 4
IL37 Q9NZH6 interleukin 37 1.2E-04 0.459 0.846 279 9
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846 277 21