Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GPC3 P51654 glypican 3 1.00 0.466 0.808 311 16
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808 307 17
TPM3 P06753 tropomyosin 3 Cellular structure 6.7E-03 0.490 0.808 297 25
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 296 24
PHGDH O43175 phosphoglycerate dehydrogenase Enzyme 1.3E-04 0.484 0.885 288 33
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846 285 9
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808 283 15
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769 281 380
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769 278 6
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846 266 96
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731 265 11
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808 261 41
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 260 410
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808 259 19
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846 243 42
IRF6 O14896 interferon regulatory factor 6 Transcription factor 1.00 0.486 0.769 233 43
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808 231 21
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808 230 39
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654 228 14
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 227 42
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731 223 32
PAFAH1B1 P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 1.00 0.504 0.769 219 103
TBC1D24 Q9ULP9 TBC1 domain family member 24 Enzyme modulator 1.3E-08 0.530 0.808 218 39
PLEC Q15149 plectin Cellular structure 8.3E-12 0.523 0.808 218 35