Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 1011 29
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 999 26
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 994 8
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 990 7
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 983 56
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 979 70
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 972 97
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 957 6
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 953 13
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 951 4
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 942 62
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 935 11
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
IL2 P60568 interleukin 2 0.48 0.336 0.885 894 4
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 852 49
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 839 55
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 839 21
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 826 38
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 816 57
LEP P41159 leptin 0.46 0.349 0.846 807 13
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 765 17
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 762 56