Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 994 8
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 1077 12
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1029 4
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1034 19
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923 990 7
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 972 97
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 957 6
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 953 13
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 979 70
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 942 62
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 951 4
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 935 11
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 926 22
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 932 19
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 839 21
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 826 38
IL2 P60568 interleukin 2 0.48 0.336 0.885 894 4
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 816 57
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 765 17
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 839 55
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 852 49
LEP P41159 leptin 0.46 0.349 0.846 807 13
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 762 56