Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 823 34
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 770 23
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
MIR21 microRNA 21 0.363 0.846 726 2
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 783 28
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962 724 33
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 765 43
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 747 2600
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 672 82
IFNA1 P01562 interferon alpha 1 0.371 0.923 662 6
VIM P08670 vimentin 0.71 0.372 0.846 644 6
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 703 681
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 686 27
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 703 97
IFNA13 P01562 interferon alpha 13 0.374 0.923 646 4
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 679 45
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 653 35
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 623 23
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 706 308
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 656 3066
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885 632 0
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 626 7