Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
SERPING1 P05155 serpin family G member 1 Enzyme modulator 0.96 0.507 0.769 21 38
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 48 35
PGM1 P36871 phosphoglucomutase 1 5.1E-15 0.628 0.577 13 35
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846 18 33
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885 32 32
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885 28 32
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 11 32
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 115 30
PC P11498 pyruvate carboxylase Enzyme 1.4E-02 0.515 0.808 15 29
DBT P11182 dihydrolipoamide branched chain transacylase E2 Enzyme 1.0E-05 0.638 0.462 14 28
ECHS1 P30084 enoyl-CoA hydratase, short chain 1 Enzyme 8.8E-04 0.601 0.654 15 26
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923 23 24
DSC2 Q02487 desmocollin 2 Cell adhesion 5.2E-08 0.610 0.538 8 24
AIFM1 O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 1.00 0.527 0.769 26 23
KNG1 P01042 kininogen 1 Enzyme modulator 3.2E-10 0.481 0.885 56 22
PYGL P06737 glycogen phosphorylase L Enzyme 1.7E-17 0.705 0.423 9 22
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 59 21
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 54 21
SUOX P51687 sulfite oxidase 9.4E-07 0.638 0.615 9 21
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 61 19
GANAB Q14697 glucosidase II alpha subunit Enzyme 1.00 0.716 0.423 10 17
UBA5 Q9GZZ9 ubiquitin like modifier activating enzyme 5 Enzyme 2.5E-04 0.582 0.731 17 16
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885 16 16
NREP Q16612 neuronal regeneration related protein 5.6E-03 0.682 0.577 9 16