Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ARNT P27540 aryl hydrocarbon receptor nuclear translocator Transcription factor 1.00 0.575 0.692 21 7
GDI1 P31150 GDP dissociation inhibitor 1 Enzyme 0.99 0.572 0.654 13 8
CHRM3 P20309 cholinergic receptor muscarinic 3 G-protein coupled receptor 0.99 0.464 0.885 17 12
ERN1 O75460 endoplasmic reticulum to nucleus signaling 1 Kinase 0.99 0.513 0.808 16 5
GCLM P48507 glutamate-cysteine ligase modifier subunit Enzyme 0.99 0.588 0.846 11 0
NR2F2 P24468 nuclear receptor subfamily 2 group F member 2 Nuclear receptor 0.99 0.575 0.692 15 10
PLS3 P13797 plastin 3 Cellular structure 0.99 0.656 0.500 10 3
IRAK1 P51617 interleukin 1 receptor associated kinase 1 Kinase 0.99 0.506 0.808 19 1
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846 17 1
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 48 35
SENP2 Q9HC62 SUMO specific peptidase 2 Enzyme 0.98 0.663 0.577 7 6
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885 16 16
TUBA1A Q71U36 tubulin alpha 1a Cellular structure 0.97 0.597 0.769 9 44
USP5 P45974 ubiquitin specific peptidase 5 Enzyme 0.96 0.670 0.577 6 1
SERPING1 P05155 serpin family G member 1 Enzyme modulator 0.96 0.507 0.769 21 38
SNX18 Q96RF0 sorting nexin 18 0.96 0.839 0.077 6 1
TMEM164 Q5U3C3 transmembrane protein 164 0.94 0.792 0.154 7 1
PPTC7 Q8NI37 protein phosphatase targeting COQ7 Enzyme 0.94 0.839 0.077 6 0
PAN2 Q504Q3 poly(A) specific ribonuclease subunit PAN2 Enzyme 0.94 0.760 0.231 8 2
MDH1 P40925 malate dehydrogenase 1 Enzyme 0.93 0.682 0.538 10 0
ATOH8 Q96SQ7 atonal bHLH transcription factor 8 Enzyme 0.91 0.711 0.346 6 1
PNRC1 Q12796 proline rich nuclear receptor coactivator 1 0.91 0.769 0.269 6 1
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885 54 21
NR1H3 Q13133 nuclear receptor subfamily 1 group H member 3 Nuclear receptor 0.90 0.566 0.692 9 5