Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
CAMKK2 Q96RR4 calcium/calmodulin dependent protein kinase kinase 2 Kinase 9.2E-02 0.617 0.654 1 1
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 1 0
ARAF P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 0.96 0.619 0.654 1 0
PRKCQ Q04759 protein kinase C theta Kinase 0.30 0.636 0.654 1 0
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 5 5
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692 4 1
PKN1 Q16512 protein kinase N1 Kinase 0.20 0.647 0.692 3 1
ROR1 Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 1.00 0.552 0.731 6 2
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731 2 3
PAK3 O75914 p21 (RAC1) activated kinase 3 Kinase 0.99 0.569 0.731 2 2
MAPK9 P45984 mitogen-activated protein kinase 9 Kinase 7.0E-02 0.561 0.731 2 0
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731 2 0
PIM1 P11309 Pim-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.482 0.769 1 0
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769 1 0
RIPK1 Q13546 receptor interacting serine/threonine kinase 1 Kinase 7.9E-03 0.479 0.769 1 3
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 7 15
PRKDC P78527 protein kinase, DNA-activated, catalytic subunit Kinase 1.00 0.540 0.808 5 5
TAF1 P21675 TATA-box binding protein associated factor 1 Kinase 1.00 0.581 0.808 3 5
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808 1 0
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 17 14
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 10 32
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846 3 2
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846 3 9
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846 2 0