Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IFNG P01579 interferon gamma 0.47 0.288 0.962 91
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 83
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 27
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 86
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 85
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 95
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 53
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 51
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 100
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 60
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 118
ALB P02768 albumin Transporter 0.64 0.317 0.962 15
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 84
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 32
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885 1
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 64
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 39
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885 20
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 84
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885 2
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 71