Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
UBE2K P61086 ubiquitin conjugating enzyme E2 K 0.99 0.631 0.654 58 0
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692 151 6
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 109 243
NEDD8 Q15843 NEDD8 ubiquitin like modifier Nucleic acid binding 0.85 0.576 0.692 88 2
PODXL O00592 podocalyxin like 1.0E-03 0.551 0.731 156 5
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769 209 39
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769 164 68
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769 150 18
GRIK2 Q13002 glutamate ionotropic receptor kainate type subunit 2 Ion channel 1.00 0.561 0.769 130 17
FBXO7 Q9Y3I1 F-box protein 7 5.8E-07 0.650 0.769 76 51
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808 356 58
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 319 157
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808 279 101
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808 241 8
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808 235 0
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 231 74
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808 161 15
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 462 173
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 437 42
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846 409 88
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 337 33
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846 287 4
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846 270 7
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846 268 0