Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GPR37 O15354 G protein-coupled receptor 37 G-protein coupled receptor 3.4E-04 0.716 0.385 23 3
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
PODXL O00592 podocalyxin like 1.0E-03 0.551 0.731 156 5
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692 151 6
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 337 33
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 469 292
SBNO2 Q9Y2G9 strawberry notch homolog 2 Enzyme 7.1E-03 0.663 0.538 41 12
UBE2L6 O14933 ubiquitin conjugating enzyme E2 L6 Enzyme 7.7E-03 0.716 0.423 19 1
PNOC Q13519 prepronociceptin Signaling 1.5E-02 0.603 0.577 103 1
TBP P20226 TATA-box binding protein Transcription factor 1.5E-02 0.552 0.846 158 3
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769 150 18
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500 116 15
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 668 32
LTA P01374 lymphotoxin alpha Signaling 0.20 0.434 0.885 353 26
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 409 13
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692 109 243
PRKRA O75569 protein activator of interferon induced protein kinase EIF2AK2 Kinase 0.42 0.579 0.615 113 9
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577 128 12
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 437 42
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808 161 15
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 616 11
UBE2L3 P68036 ubiquitin conjugating enzyme E2 L3 Enzyme 0.84 0.644 0.615 56 39