Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GPX3 P22352 glutathione peroxidase 3 Enzyme 5.1E-02 0.522 0.769 27 0
ANXA4 P09525 annexin A4 1.2E-08 0.599 0.692 26 2
FOSB P53539 FosB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.98 0.463 0.846 26 0
ANXA2 P07355 annexin A2 9.8E-05 0.453 0.808 26 0
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846 25 185
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 24 2
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731 24 2
MALAT1 metastasis associated lung adenocarcinoma transcript 1 0.435 0.846 23 0
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808 22 62
NCOR1 O75376 nuclear receptor corepressor 1 Transcription factor 1.00 0.597 0.731 22 7
MACIR Q96GV9 macrophage immunometabolism regulator 0.43 0.691 0.462 20 5
KRT18 P05783 keratin 18 0.73 0.530 0.692 19 5
NR1I3 Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 3.5E-08 0.448 0.846 19 1
TRMT11 Q7Z4G4 tRNA methyltransferase 11 homolog 3.9E-12 0.729 0.269 18 2
XPA P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 7.9E-05 0.520 0.846 17 46
GNMT Q14749 glycine N-methyltransferase 2.8E-03 0.626 0.462 17 4
IL12A P29459 interleukin 12A 4.7E-02 0.491 0.808 17 4
PHGDH O43175 phosphoglycerate dehydrogenase Enzyme 1.3E-04 0.484 0.885 16 32
SLC40A1 Q9NP59 solute carrier family 40 member 1 Transporter 0.99 0.570 0.731 16 22
FST P19883 follistatin Enzyme modulator 0.98 0.513 0.731 16 0
LARGE1 O95461 LARGE xylosyl- and glucuronyltransferase 1 Enzyme 0.99 0.526 0.654 15 14
SCD O00767 stearoyl-CoA desaturase 0.97 0.490 0.808 15 1
MACROD2 A1Z1Q3 mono-ADP ribosylhydrolase 2 0.43 0.686 0.423 13 45
PSMA4 P25789 proteasome 20S subunit alpha 4 0.60 0.716 0.385 13 22