Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 2724 31
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 1456 27
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 1206 36
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 1074 19
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 1059 13
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 859 12
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 765 43
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 731 141
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923 686 27
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 654 55
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846 649 19
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 647 7
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923 635 7
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 633 29
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885 531 41
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 528 10
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 496 96
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808 357 14
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846 321 5
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808 318 6
DCN P07585 decorin 0.31 0.457 0.808 297 6
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846 288 1